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Nicola Fallon, the girl in a coma, reaches crisis point, and her parents face an agonising decision.
Simon Harwood the heart recipient is back in, with a worsening condition, and Nick fears he is rejecting the new heart and puts him on immuno-suppressive drugs, but Anton Meyer diagnoses it as an infection and changes the medication to antibiotics.
Ruth Reynolds is back in Holby for a heart operation, which causes her to consider the future for her adopted daughter.
Paul Ripley spends a lot of time at Nicola Fallon's bedside, to the anger of her parents.
Luke Mably [ Ward Clerk Paul Ripley ], Claire Goose [ Tina Seabrook ], Bryan Murray [ Mr.
Julie Fitzjohn helps a young mother with a heart-breaking dilemma.
Meanwhile, the pressure builds up for house officer Victoria Merrick, after she saves the life of a patient, Chris Woodhouse, and she resorts to taking drugs at work.
Lizzie is a motor-bike racer, recovering after an accident, and is visited by her husband Dave, but she becomes suspicious when she sees him riding off with another woman, Mel.
Joanna Kirkland [ Nicola Fallon ], Simon Molloy [ Mr. Fallon ], Kevin Doyle [ Simon Harwood ], Isobel Middleton [ Anne Harwood ], Malcolm Rogers [ Dennis Johnson ], Billy Carter [ Shane Johnson ], Daniel Roberts [ Colin ] Kirstie Collins catches Nick Jordan in a compromising situation with Ellie Sharpe in a linen cupboard.
Fraser James [ Peter Ellis ], June Watson [ Ruth Reynolds ], Mary Jo Randle [ Marie ], Simon Chandler [ Adrian Walker ], Aline Mowat [ Jackie Walker ], Nick Dunning [ Mark Simpson ], Danny Cunningham [ Tom Woodley ], Mary Healey [ Frances Woodley ], Terence Rigby [ Len Woodley ], Amy Robbins [ Osla ], Jamie Sives [ Ellie's ex-boyfriend ], Valentine Nonyela [ Ronnie Cornwell ], Valerie Murray [ Rose Cornwell ], Alex Avery [ Carl ] Julie Fitzjohn has been sacked from her other, part-time job at a supermarket, which she has taken to make ends meet.
Anton Meyer tells Victoria Merrick that patient Chris Moorhouse is ogin to sue the hospital, because his voice has not recovred.
When Tom dies, Nick has to help the relatives deciode whether some of his organs can be used for transplant.